Custom Services

Custom Antibody Discovery

Contact us and let’s elevate your company’s success with our advanced monoclonal antibody discovery service. From custom reagent antibodies to potential therapeutic candidates, we can scale the project to fit your needs. Our cutting-edge process involves isolating antibodies from cloned single B cells obtained from immunized rabbits. The resulting antibodies are cloned, sequenced and recombinantly expressed and can be screened for your desired characteristics. Embrace a collaborative partnership with us, where flexibility is key. We adapt to your workflow, providing support and expertise to navigate the complexities of developing custom monoclonal antibodies. Over the years, we’ve successfully assisted numerous organizations in achieving their antibody-related goals. Embark on a transformative journey by initiating a discussion with us today. Discover how our expertise can seamlessly integrate with the unique needs of your organization. Contact us and let’s unlock the potential of antibody discovery together.

Cell Sorting (FACS)

Discover cutting-edge cell sorting services right here in the heart of Seattle! Cobalt Biologics proudly presents a state-of-the-art cell sorting experience with the Beckman Coulter CytoFlex SRT FACS instrument, equipped with three lasers and ten colors. Whether you’re diving into bulk sorts, plate sorts in various formats, or single-cell sorting, our instrument ensures precision and reliability. Navigate your cell sorting journey with the support of our expertly trained technician, ready to assist you every step of the way. Whether you’re a beginner exploring the world of cell sorting or a seasoned professional seeking advanced capabilities, we tailor our services to meet your unique needs. For detailed insights into our capabilities and competitive pricing, reach out to us today.

Molecular Biology and Other Lab Services

Are you at the outset of establishing a virtual biotech venture and searching for access to a fully equipped laboratory complemented by a dedicated staff? The availability of such resources is pivotal for executing your initial proof-of-concept experiments, generating vital data crucial for propelling your company forward. If your current situation aligns with this need, our support is tailored to transform your vision into tangible results. Within our well-equipped laboratory, we offer a spectrum of advanced techniques to facilitate your research journey. From proficient tissue culture and in vitro assays to extensive applications in molecular biology, protein expression and purification, biolayer interferometry, ELISAs, flow cytometry, and FACS, our capabilities span a diverse array of scientific methodologies. Reach out to us and explore how our comprehensive lab services can contribute to the accelerated growth of your startup company. Let’s collaborate to turn your innovative ideas into impactful achievements.

Antibody Production

Advance your projects with our comprehensive antibody production service tailored to your specific needs. Whether you’re seeking an antibody referenced in clinical studies, patents, or the literature, our years of expertise in producing reference antibodies for diverse organizations make us the ideal partner for your internal research initiatives. Even if you lack knowledge of antibody sequences, our adept experts can step in and work to determine them for you. This not only facilitates the benchmarking of your clinical candidates but also enables a comparative analysis against potential competitor antibodies. Our production capabilities extend to diverse formats and scaffolds, accommodating specific requirements such as species, isotype, antibody fragments, or advanced bispecific and multispecific platforms. Tailoring the quantity of antibodies to meet your project’s unique demands is a cornerstone of our flexibility and experience. Reach out to us, and let’s explore how our expertise and adaptability can seamlessly align with your project’s objectives. Uncover the possibilities in antibody production as we work together to advance your research initiatives.

Antibody Engineering and Humanization

Unlock the full potential of your antibodies with our advanced antibody engineering and humanization services. With a wealth of capabilities and extensive experience, we seamlessly navigate the spectrum from relatively straightforward tasks, such as altering species or isotypes, to more intricate endeavors like creating bispecifics, multispecifics, antibody fragments, and fusions. Our expertise extends beyond mere modification, encompassing a thorough analysis of your clinical candidates. We specialize in identifying and addressing potential concerns, such as free cysteines, N-linked glycosylation sites, deamidation, oxidation, and isomerization sites. Dive into the realm of antibody humanization with confidence, backed by our proven track record. Our portfolio includes the humanization of the only fully FDA-approved and marketed humanized rabbit antibody, along with several other humanized antibodies at various clinical stages. Elevate your antibody development journey by connecting with us. Let’s explore how our services can transform your antibodies, enhancing your chances of achieving success in your research endeavors.

Protein Production

Revolutionize your research with our protein production services, meticulously crafted to meet your unique specifications. Whether you envision a receptor extracellular domain fused to a specific species Fc, a bespoke non-human primate protein, or a protein tailored for an assay or animal immunization campaign, our experts are equipped to bring your vision to life. From growth factors and cytokines to viral surface proteins, neuropeptides, cytoplasmic proteins, and tethered receptor-ligand pairs – we’ve successfully produced a diverse array of proteins for our esteemed clients. Customization is at the core of our service. Imagine proteins designed precisely for your applications – we offer modifications such as site-specific biotinylation to ensure your proteins align seamlessly with your research goals. Embark on an accelerated research journey by reaching out to us. Contact us today for more information and let’s explore how our protein production expertise can catalyze advancements in your scientific pursuits.

The good thing about science is that it’s true whether or not you believe in it.

Neil deGrasse Tyson

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Introducing - Custom Services!

We have been providing unparalleled antibody services and customized molecular biology solutions for many external partners over the years. While our reputation has predominantly thrived on the organic spread of positive experiences, we are now thrilled to officially showcase our comprehensive suite of services.