Anti-human CD37 Recombinant Antibody

Human CD37 antibody that is potent and highly specific. Binds strongly to CD19+ positive B cells and weakly but significantly to some T cells and myeloid cells. Verified to work in non-human primate CD37 as well.

Catalog Items:

  • # 201401 – Rabbit IgG, kappa – 50 µg – $79
  • # 201402 – Mouse IgG2a, kappa NullFc™ – 50 µg – $79
  • # 201402 – Biotinylated rabbit Fab – 50 µg – $99

$79.00$99.00

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SKU N/A Category

Specifications

Clone XA1531
Discovery Method Rabbits were immunized with HEK293 cells expressing human CD37, and antigen-positive B cells were single-cell sorted. The variable domain sequences were cloned, sequenced, and subcloned into expression vectors containing the various species and isotype constant domains
Available Formats Rabbit IgG/kappa; Mouse IgG2a/kappa with NullFc™ (compatible with traditional anti-mouse secondary reagents); Biotinylated rabbit Fab with a single defined biotin and His-tag at the C-terminus of the heavy chain
Host Species Rabbit
Immunogen Human CD37 (accession NM_001774) recombinantly expressed on HEK293 cells
Verified Reactivity Human, cynomolgus monkey (Macaca fascicularis)
Verified Applications Flow Cytometry
Concentration 0.5 mg/ml
Production Transient transfection expression system in mammalian HEK293 cells
Purification Protein A affinity chromatography (MAb), Immobilized metal ion chromatography (Fab)
Formulation PBS pH 7.2 with 0.08% sodium azide
Storage 4° C for up to 3 months, for longer storage aliquot and store at -20° C
Target CD37
Alternate Names GP52-40, TSPAN26
Target Description CD37 is a type II transmembrane protein in the tetraspanin family. CD37 associates with integrins and other transmembrane 4 family members. CD37 is expressed highly in B cells and also at a low level in myeloid cells and T cells.
Uniprot P11049

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